VS110 in research |
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 Archiving rare and valuable
biological sections
Sharing specimen via the web for
discussion, presentation or
teleconferencing
Building online databases for
students education
Setting up application-oriented
reference databases |
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Life science research has relied heavily on advances in microscopy to move our knowledge forward. The VS110 system represents such a step forward, offering excellent throughput for extensive image analysis and superb documentation of tissue sections, cell cultures and even tissue microarrays.
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 Global discussion
Tissue microarrays
Specialised analysis
Object detection
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Global discussion
 Due to the unique way the images are stored and transmitted, a researcher can invite the rest of their group to view slides of interest, either individually or as a group, whether they are in the same building or situated around the world. The virtual facility offers controllable access for the user, such that with the correct permissions, they can add and edit files.
Tissue microarrays
 The functionality of the VS110 system can be expanded with a dedicated TMA software module, facilitating acquisition and simple analysis of tissue microarrays. This module enables documentation of each core separately, accurately recording its slide and core reference for traceability, and automatically storage and upload to the Net Image Server SQL database.
Specialised analysis
 The VS110 software enables simple measurements such as perimeters, distances and areas without the need for scaling. With additional software tools, a number of analysis functions are available to aid in the rapid investigation of the virtual slides. For example, the family of software can perform phase analysis to automatically calculate the share of specific tissue types or to identify structures according to a series of criteria such as size, shape and intensity.
Object detection
 The Scope software package can be installed on the VS110 workstation or different workstations, connected via a local network. The combination of VS110 with the Scope analysis software allows a full image analysis to be carried out with the help of a workflow-oriented user interface. The user is guided through a logical multi-step procedure, consisting of image processing, object detection, feature extraction and data analysis by sophisticated gating and classification schemes that are derived from cytometry. The powerful object detection module is optimised to segment nuclei, cells or other structures, and several detection algorithms can be selected and adapted to the objects of interest. Relevant object features and properties can be selected out of a comprehensive list of parameters. The selected features will be measured for each detected object. Additionally mathematical operations and calculations can be performed on these measurements. This highly flexible data output enables the system to be used for almost all current and future cell-based assays.
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