Experience Gold Standard Precision with EBUS-TBNA: The Minimally Invasive Solution for Lung Cancer Diagnosis

Endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) is a reliable and well-established technique used in lung cancer diagnosis and staging, offering unmatched precision and accuracy. Not only does EBUS-TBNA provide reliable diagnostic results, but it also ensures patient safety with a non-surgical approach, reducing the risks associated with more invasive procedures. As the preferred method for lung cancer testing worldwide, EBUS-TBNA continues to set the benchmark for excellence in pulmonary care.

20 Years of EBUS

2004
World´s first EBUS bronchoscope and 22G needle launched

2006
EBUS-TBNA adopted for minimally invasive lung cancer diagnosis & staging

2013
International Guidelines recommend EBUS-TBNA4

2024
Let´s celebrate #20YearsOfEBUS

95,7%
Sensitivity in diagnosing malignant nodes1

98%
Accuracy in mediastinal lymph node staging2

91%
Precision in lesion diagnoses3

2016
Comprehensive needle portfolio

Slim EBUS Bronchoscope

The BF-UC290F is the third generation of the reliable Olympus EBUS-TBNA endoscope. It enables enhanced access and control to allow staging and diagnosis of even difficult-to-reach lymph nodes and lesions. 2

  • Powerful angulation: Up to 160° angulation for enhanced access to challenging target sites
  • Unique compact distal tip: Only 6.6 mm outer diameter and shorter rigid part of 25 mm for improved maneuverability
  • Increased puncture performance: 5° steeper puncture angle for smooth penetration of the bronchial wall

This impressive EBUS-TBNA endoscope enables a wider field of application with its compact size while maintaining the large 2.2 mm working channel and the compatibility to the full needle portfolio.

Ultrasound Processor EU-ME3

With more functions, better visualisation, and enhanced operability, the EU-ME3 high-quality, high-resolution, compact ultrasound processor enables integration with conventional endoscopy on a single workstation. Its advanced features include Tissue Harmonic Echo (THE), Contrast Harmonic EUS (CH-EUS), and Elastography.

The EU-ME3 ultrasound processor is unique in its ability to support a wide range of Endobronchial Ultrasound Bronchoscopy (EBUS) procedures, such as EBUS-guided transbronchial needle aspiration (EBUS-TBNA) and radial EBUS for peripheral bronchoscopy procedures.

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A Needle for Every Situation

Olympus offers 19G EBUS-TBNA needless in addition to the 21G, 22G and 25G needles. But now it also provides the second generation of EBUS needles – the Vizishot2.
While the entire portfolio offers the already established safety mechanisms and excellent ultrasound visibility. Olympus now provides a needle for every situation – expanding your possibilities in EBUS-TBNA.

ViziShot 2 FLEX 19G – Advancing Histology Sampling in EBUS-TBNA

The largest EBUS needle in the Olympus portfolio, with a 19G diameter with FNA (fine needle aspiration) and FNB (fine needle biopsy) indication.
ViziShot 2 FLEX 19G supports histological sampling for suspected sarcoidosis and lymphoma but also helps to provide more tissue for advanced molecular analyses enabling targeted lung cancer therapy.

Key Evidence and Benefits:

  • Improving tissue quantity6 – getting the right diagnosis7
  • High needle flexibility – Easy access to challenging lymph nodes and stations7
  • Puncture with confidence – Clear ultrasound visibility and high user satisfaction8

The Olympus EBUS Solution – Supporting Reliable Staging and High Yield

EBUS-TBNA has proven to be of great value not only for lymph node staging (N-staging) but also for the strategic use of cytology and histology samples for molecular analysis. The acquired specimen can be used to obtain a reliable diagnosis as well as for cell-block preparation, immunochemistry, and molecular studies.

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References

1. Real-time Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration of Mediastinal and Hilar Lymph Nodes
https://journal.chestnet.org/article/S0012-3692(15)32904-4/abstract
Chest Journey Volume 126, Issue 1 p122-128 July 2004
Kazuhiro Yasufuku, MD ∙ Masako Chiyo, MD ∙ Yasuo Sekine, MD ∙ Prashant N. Chhajed, MD, FCCP ∙ Kiyoshi Shibuya, MD ∙ Toshihiko Iizasa, MD ∙ Takehiko Fujisawa, MD

2. Comparison of Endobronchial Ultrasound, Positron Emission Tomography, and CT for Lymph Node Staging of Lung Cancer
https://journal.chestnet.org/article/S0012-3692(15)52783-9/abstract
Volume 130, Issue 3 p710-718 September 2006
Kazuhiro Yasufuku, Takahiro Nakajima, Ken Motoori, Yasuo Sekine, Kiyoshi Shibuya, Kenzo Hiroshima, Takehiko Fujisawa

3. Transbronchial vs Transesophageal Needle Aspiration Using an Ultrasound Bronchoscope for the Diagnosis of Mediastinal Lesions
https://journal.chestnet.org/article/S0012-3692(15)38351-3/abstract
Volume 147, Issue 5 p1259-1266 May 2015
Masahide Oki, Hideo Saka, Masahiko Ando, Rie Tsuboi, Masashi Nakahata, Saori Oka, Yoshihito Kogure, Chiyoe Kitagawa

4. Guideline for the acquisition and preparation of conventional and endobronchial ultrasound-guided transbronchial needle aspiration specimens for the diagnosis and molecular testing of patients with known or suspected lung cancer
https://pubmed.ncbi.nlm.nih.gov/25377908/5
2014;88(6):500-17.10.1159/000368857. 2014 Nov 5.
Erik H F M van der Heijden , Roberto F Casal, Rocco Trisolini, Daniel P Steinfort, Bin Hwangbo, Takahiro Nakajima, Birgit Guldhammer-Skov, Giulio Rossi, Maurizio Ferretti, Felix F J Herth, Rex Yung, Mark Krasnik;

5. Human Ex Vivo Lung Evaluation of the Next Generation Convex Probe Endobronchial Ultrasound Bronchoscope
https://journal.chestnet.org/article/S0012-3692(17)32436-4/fulltext
Volume 152, Issue 4, Supplement 884, October 2017
Kosuke Fujino ∙ Hideki Ujiie ∙ Hitoshi Igai ∙ Tomonari Kinoshita ∙ Changyoung Lee ∙ Salma Hindy ∙ Andrew Effat ∙ Kazuhiro Yasufuku

6. Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration: Techniques and Challenges
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343395/
2019 Jan-Mar;36(1):65–70.
Valliappan Muthu, Inderpaul Singh Sehgal, Sahajal Dhooria, Kuruswamy T Prasad, Nalini Gupta, Ashutosh N Aggarwal, Ritesh Agarwal

7. Flexible 19-Gauge Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration Needle: First Experience
https://karger.com/res/article/94/1/52/290770/Flexible-19-Gauge-Endobronchial-Ultrasound-Guided
May (2017) 94 (1): P52–57.
Chung Tyan, Priya Patel, Kasia Czarnecka, Daniela Gompelmann, Ralf Eberhardt, Marc Fortin, Paul MacEachern, Christopher A.Hergott, Elaine Dumoulin, Alain Tremblay, Samuel V.Kemp, Pallav L.Shah, Felix J.F. Herth, Kazuhiro Yasufuku

8. A novel flexible 19G EBUS-TBNA needle: Absolute and relative performance in patients
https://erj.ersjournals.com/content/48/suppl_60/pa2036.abstract
2016 48: PA2036; DOI: 10.1183/13993003.PA2036
Anna Sczaniecka, Xavier Gonzalez, Lina Zuccatosta, Stefano Gasparini, Daniela Gompelmann, Felix Herth, Samuel Kemp, Pallav Shah, Maciej Gnass, Artur Szlubowski

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