The Gold Standard for Lung Cancer Staging 1

Endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) is a reliable and well-established technique that enables the visualisation and sampling of mediastinal, central and hilar lesions and lymph nodes within the tracheobronchial tree.
With the EBUS bronchoscope inserted into the trachea or the esophagus, the accessible lymph node stations can be explored and the lesions outlined while offering you the freedom to select from different EBUS needle lineups and sizes depending on your needs.

15 Years EBUS-TBNA

First publication with description
of EBUS-TBNA principle

Evolution of lung cancer diagnosis:
EBUS-TBNA samples for molecular testing

International guidelines
recommend EBUS-TBNA as
first testing method for lung cancer8

15 years
proven performance

More than
of studies on EBUS-TBNA
were performed with the Olympus
EBUS system and Olympus needles7

2018: Innovations for EBUS-TBNA –
Expand your possibilities in EBUS-TBNA

Slim EBUS Bronchoscope

The BF-UC290F is the third generation of the reliable Olympus EBUS-TBNA endoscope. It enables enhanced access and control to allow staging and diagnosis of even difficult-to-reach lymph nodes and lesions. 2

  • Powerful angulation: Up to 160° angulation for enhanced access to challenging target sites
  • Unique compact distal tip: Only 6.6 mm outer diameter and shorter rigid part of 25 mm for improved maneuverability
  • Increased puncture performance: 5° steeper puncture angle for smooth penetration of the bronchial wall

This impressive EBUS-TBNA endoscope enables a wider field of application with its compact size while maintaining the large 2.2 mm working channel and the compatibility to the full needle portfolio.

Ultrasound Processor EU-ME3

With more functions, better visualisation, and enhanced operability, the EU-ME3 high-quality, high-resolution, compact ultrasound processor enables integration with conventional endoscopy on a single workstation. Its advanced features include Tissue Harmonic Echo (THE), Contrast Harmonic EUS (CH-EUS), and Elastography.

The EU-ME3 ultrasound processor is unique in its ability to support a wide range of Endobronchial Ultrasound Bronchoscopy (EBUS) procedures, such as EBUS-guided transbronchial needle aspiration (EBUS-TBNA) and radial EBUS for peripheral bronchoscopy procedures.

Read more

A Needle for Every Situation

Olympus offers a 19G EBUS-TBNA needle in addition to the 21G and 22G needles. But now the second generation of EBUS needles, ViziShot 2, are also available. While the entire portfolio offers the already established safety mechanisms and excellent ultrasound visibility, Olympus now provides a needle for every situation – expanding your possibilities in EBUS-TBNA.

ViziShot 2 FLEX 19G – Advancing Histology Sampling in EBUS-TBNA

Improved sample size for enhanced diagnostic capabilities and targeted lung cancer therapy.

Key Evidence and Benefits:

  • Improving tissue quantity 3,4 – Safely getting the right diagnosis 5
  • High needle flexibility – Easy access to challenging lymph nodes and stations 5
  • Puncture with confidence – Clear ultrasound visibility and high user satisfaction 6

The Olympus EBUS Solution – Supporting Reliable Staging and High Yield

EBUS-TBNA has proven to be of great value not only for lymph node staging (N-staging) but also for the strategic use of cytology and histology samples for molecular analysis. The acquired specimen can be used to obtain a reliable diagnosis as well as for cell-block preparation, immunochemistry, and molecular studies.


Are you interested in Olympus products for EBUS-TBNA? Send us a request and an Olympus consultant will contact you.

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Clinical Evidence

Further clinical references and abstracts are available in the download section.

  1. 1.Combined endobronchial and esophageal endosonography for the diagnosis and staging of lung cancer: European Society of Gastrointestinal Endoscopy (ESGE) Guideline, in cooperation with the European Respiratory Society (ERS) and the European Society of Thoracic Surgeons (ESTS) Endoscopy 2015; 47(06): 545–559 Peter Vilmann, Paul Frost Clementsen, Sara Colella, Mette Siemsen, Paul De Leyn, Jean-Marc Dumonceau, Felix J. Herth, Alberto Larghi, Enrique Vazquez-Sequeiros, Cesare Hassan, Laurence Crombag, Daniël A. Korevaar, Lars Konge, Jouke T. Annema
  2. 2.Human Ex Vivo Lung Evaluation of the Next Generation Convex Probe Endobronchial Ultrasound Bronchoscope. CHEST Journal 2017;152(4):A884 Fujino K, Ujiie H, Igai H, Kinoshita T, Lee C, Hindy S, Effat A, Yasufuku K.
  3. 3.Advancements in lung cancer diagnosis and treatment CHEST Annual Meeting, Los Angeles, 2016 Parthiban, S et al.
  4. 4.Endobronchial Ultrasound-Guided TBNA (EBUS-TBNA) with a 19 Gauge Needle – First Experience American Thoracic Society International Conference, Denver, 2015; B103 Herth, FJF et al.
  5. 5.Flexible 19 Gauge Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration – First Canadian Experience American Thoracic Society International Conference, Denver, 2015; B42 Tyan, C et al.
  6. 6.A Novel Flexible 19G EBUS-TBNA Needle: Absolute and Relative Performance in Patients European Respiratory Journal, 2016; 48: 6 Sczaniecka, A et al.
  7. 7.Added value of combined endobronchial and oesophageal endosonography for mediastinal nodal staging in lung cancer: a systematic review and meta-analysis Lancet Respir Med. 2016 Dec;4(12):960-968. doi: 10.1016/S2213-2600(16)30317-4. Epub 2016 Oct 20. Daniël A Korevaar, Laurence M Crombag et al.
  8. 8.Guideline for the acquisition and preparation of conventional and endobronchial ultrasound-guided transbronchial needle aspiration specimens for the diagnosis and molecular testing of patients with known or suspected lung cancer Respiration. 2014;88(6):500-17. doi: 10.1159/000368857. Epub 2014 Nov 5. Erik H F M van der Heijden, Roberto F Casal, Rocco Trisolini et al.